REGENTS OF THE UNIVERSITY OF MINNESOTA
This is an administrative supplement providing additional funds to allow us to accelerate our analysis of target antigens in protection and T cell assays. These experiments fall within the scope of Specific Aims 2 and 3 as described in the original application. Additional funds were requested for equipment and personnel in order to rapidly translate our proteomic analysis in a priority list of vaccine antigens. It is important to accelerate the tempo of this aspect of our application so that we rapidly uncover the most important antigens that could then be examined as a multi-valent vaccine in pre-clinical studies.