The North Central Cancer Treatment Group (NCCTG) has need of Information Technology (IT) resources to support the development and integration of standardized IT tools to reduce the administrative burden on study investigators. The NCCTG IT staff is currently supporting the Oncology Patient Enrollment Network (OPEN) implementation and will soon need to integrate the new version of the NCI Common Terminology Criteria for Adverse Events (CTCAEv4), and adopt an electronic Remote Data Capture/Clinical Data Management System (RDC/CDMS). Existing NCCTG IT staff is fully committed to multiple high priority projects and additional FTE is required to implement the above mentioned items in a timely manner. The effort associated with OPEN has already begun and is expected to continue for 12 months, with decreasing effort after the 3rd quarter of 2009. The CTCAEv4 conversion will take place during the 3rd and 4th quarters of 2009. The RDE/CDMS integration is expected to begin 4th quarter of 2009 and require significant effort for several years. A total of 0.63 FTE of a Programmer/Analyst for two (2) years is requested to partially offset the costs associated with these projects. A description of effort associated with each project follows. OPEN: The NCCTG has developed and is testing its "node" for communicating patient registration information with the CTSU. However, rolling out currently open (approximately 4-6 studies) and soon-to-be open studies will require additional IT effort. Each new study will require that the study eligibility checklist be tested and accurately generated in both the OPEN and NCCTG systems, that the study registration process be fully tested end-to-end, and that identified "bugs" are corrected. CTCAEv4: The NCI is implementing version 4 of the CTCAE in the next few months requiring that a new library be added to the NCCTG Enterprise Syste, electronic forms be modified, and reporting labels,libraries be implemented. Additionally, any on-going studies that need to change from the current CTCAE version to version 4 will require significant effort requiring an analysis of how best to make the change, ie, convert data in the master data base or, alternatively, on the reporting side, either of which will require programming resources to implement. RDE/CDMS: The NCCTG will be adopting/integrating the NCI-procured RDE/CDMS over the next several years. This activity will require significant IT project planning/management, analysis, design, testing, and implementation tasks. Analysis will be required to determine how to implement the software and critically how it will be integrated with existing NCCTG data systems, including managing security for remote data entry. Testing will be required to ensure the integrated systems are working properly, that security is appropriate, and end users are able to access and understand the system.