RUSH UNIVERSITY MEDICAL CENTER
The parent grant K23 AG030944 or Paul B. Beeson Award in Aging proposed to examine a broad set of 5 specific aims over 4 years (7/2008-6/2012) and to conduct a prospective, population-based epidemiological study of the relations of the overall self-neglect to health care utilizations and mortality in a biracial population of older adults.
The specific aims of this supplemental research are 1) to quantify the relations of specific indicators of self-neglect to the risk of mortality; and 2) to compare the relations noted above among blacks and whites in the same community. Elder self-neglect is an increasing common public health issue across all racial/ethnic groups and accounts for approximately 1.2 million cases annually within the US. Our prior research indicates that self-neglect is associated with increased risk of mortality. However, the independent contribution of the specific indicators of self-neglect to mortality among older people remains uncertain. There is no systematic information on the extent to which the specific indicators of self-neglect is associated with differential mortality risks in blacks (non-Hispanic blacks) and whites (non-Hispanic whites). This information will be critical in improved understanding of the causal relations of self-neglect with respect to adverse outcomes and will set the cornerstone for future targeted prevention and intervention studies in the general population.
The project will coordinate the record linkage of the Chicago Department on Aging (CDOA) and the Chicago Health and Aging Project (CHAP). The important design features are: 1) Rigorously defined population, higher follow-up rates of 85%, and socioeconomically diverse; 2) Available data on the exposure of interest (15 indicators of elder self-neglect) 3) Available data on mortality status in CHAP; 4) Available extensive relevant variables as potential confounders for the proposed analysis; and 5) Efficient utilization of existing resources, that permit a large, rigorous, population-based study of the mortality risk associated with the specific indicators of self-neglect.
This supplement application is within the general scope of the peer-reviewed parent Beeson application. In addition, this supplement will stimulate the economy by permitting the employment of predoctoral student Ms. Iggy E-Shien Chang and increase the existing effort of programmer and biostatistician. In addition, this supplement will permit Dr. Dong to mentor Ms Chang during her predoctoral phases toward her research development and contract additional needed skills. Furthermore, the parent Beeson award has been productive and the specific aims of this supplement fit tightly with the parent Beeson grant. Lastly, this supplement represents the logical next phase of the study and elevates the tempo of the scientific investigation.
This supplemental application aims to quantify the relations of specific indicators of self-neglect with risk of mortality and to compare the racial/ethnic differences in mortality risk. information will be critical in improved understanding of the causal relations of self-neglect with respect to adverse outcomes and will set the cornerstone for future targeted prevention and intervention studies in the general population.