EMORY UNIVERSITY

The goal of this project is the construction of a new dual function 19,800 sq ft building devoted to NHP research in two of the most rapidly growing areas of the Yerkes research portfolio that align with national health priorities -infectious disease and transplant medicine. This new facility will address major unmet needs in tuberculosis and other emerging infectious disease threats, and will further the development of immune therapies to reduce morbidity and mortality associated with bone marrow, organ, and tissue transplants. The first floor of the building will be dedicated to infectious disease research, with an ABSL3 capacity for 108 animals in 4 self-sufficient environmentally contained areas that will permit up to 4 concurrent studies, each with unique high-risk agents without danger of cross contamination. The third floor will be dedicated to the Transplant Medicine Facility, have a capacity for quarantine of 32 NHPs and housing up to 224 NHPs post transplant, will include a suite for profoundly immunocompromised animals, and a dedicated operating room for dual transplant donor/recipient surgeries. All building maintenance functions will be housed in an innovatively designed second floor interstitial space so that service and equipment maintenance functions can be performed without the need to enter either ABSL3 space or specialized space for immunocompromised animals. The air handling systems for the ABSL3 floor and the transplant floor will be entirely separated and isolated from each other to preclude the possibility of cross contamination.

Clarification of Codes