UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS
DESCRIPTION (provided by applicant): We are requesting an in vivo multiphoton microscope for the UT Southwestern Live Cell Imaging Facility (LCIF), a campus wide core facility that provides access to optical microscopy instrumentation for more than 150 researchers from 35 departments on the campus of UT Southwestern Medical Center in Dallas. This instrument will provide access to technology that currently is unavailable to researchers on the UT Southwestern campus. To accommodate imaging in live animals, explanted organs and tissue slices, we are requesting a Zeiss LSM 710 mounted on an AxioExaminer upright microscope with two Coherent Vision II Ti:Sapphire lasers. The system is configured to permit simultaneous two photon imaging and two photon photoactivation, imaging of forward directed SHG, and simultaneous imaging of backward directed SHG with two fluorescence channels. We are requesting a GaAsP detector for detecting very weak signals such as occur when imaging deep into tissue in live animals or imaging fluorescence signals where expression levels are near endogenous levels, such as in transgenic animals where the transgene is under the control of the endogenous promoter. The health-related research projects that will be enabled by the addition of this technology include studies of brain function, immune responses, wound healing, heart disease, and premature birth.
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| AWARD OVERVIEW |
| Award Number |
1S10RR029731-01 |
Funding Agency |
Department of Health and Human Services |
| Total Award Amount |
$1,190,132 |
Project Location - City |
Dallas |
| Award Date |
05/20/2010 |
Project Location - State |
TX |
| Project Status |
Completed |
Project Location - Zip |
75390-9020
|
| Jobs Reported |
0.00 |
Congressional District |
30 |
| Project Location - Country |
US |
|
|
Recipient Information
(Grants)
| Recipient Information (Grants) |
|
Recipient Name
|
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS |
| Recipient DUNS Number |
800771545
|
| Recipient Address |
5323 HARRY HINES BLVD |
| Recipient City |
DALLAS |
| Recipient State |
Texas |
| Recipient Zip |
75390-7208 |
| Recipient Congressional District |
30 |
| Recipient Country |
USA |
Required to Report Top 5
Highly Compensated Officials |
No |
Projects and Jobs Information
| Projects and Jobs Information |
| Project Title |
IN VIVO MULTIPHOTON MICROSCOPE FOR UT SOUTHWESTERN LIVE CELL IMAGING FACILITY |
| Project Status |
Completed |
| Final Project Report Submitted |
Yes |
| Project Activities Description |
Diseases, Disorders & Medical Disciplines, General/Other |
| Quarterly Activities/Project Description |
The final Total Federal Amount of ARRA Expenditure for this project is less than the Award Amount. The project was completed under budget. No more funds will be expended on this project.DESCRIPTION (provided by applicant): We are requesting an in vivo multiphoton microscope for the UT Southwestern Live Cell Imaging Facility (LCIF), a campus wide core facility that provides access to optical microscopy instrumentation for more than 150 researchers from 35 departments on the campus of UT Southwestern Medical Center in Dallas. This instrument will provide access to technology that currently is unavailable to researchers on the UT Southwestern campus. To accommodate imaging in live animals, explanted organs and tissue slices, we are requesting a Zeiss LSM 710 mounted on an AxioExaminer upright microscope with two Coherent Vision II Ti:Sapphire lasers. The system is configured to permit simultaneous two photon imaging and two photon photoactivation, imaging of forward directed SHG, and simultaneous imaging of backward directed SHG with two fluorescence channels. We are requesting a GaAsP detector for detecting very weak signals such as occur when imaging deep into tissue in live animals or imaging fluorescence signals where expression levels are near endogenous levels, such as in transgenic animals where the transgene is under the control of the endogenous promoter. The health-related research projects that will be enabled by the addition of this technology include studies of brain function, immune responses, wound healing, heart disease, and premature birth. |
| Jobs Created |
0.00 |
| Description of Jobs Created |
n/a |
Purchaser Information
(Grants)
| Purchaser Information |
| Contracting Office ID |
Not Reported |
| Contracting Office Name |
Not Available |
| Contracting Office Region |
Not Available |
| TAS Major Program |
75-0847 |
| Award Information |
| Award Date |
05/20/2010 |
| Award Number |
1S10RR029731-01 |
| Order Number |
|
| Award Type |
Grants |
| Funding Agency ID |
75 |
| Funding Agency Name |
Department of Health and Human Services |
| Funding Office Name |
Not Available |
| Awarding Agency ID |
75 |
| Awarding Agency Name |
Department of Health and Human Services |
| Amount of Award |
$1,190,132 |
| Funds Invoiced/Received |
$1,188,608 |
| Expenditure Amount |
$1,188,608 |
| Infrastructure Expenditure Amount |
$0 |
| Infrastructure Purpose and Rationale |
Not Reported |
| Infrastructure Point of Contact Name |
Not Reported |
| Infrastructure Point of Contact Email |
Not Reported |
| Infrastructure Point of Contact Phone |
Not Reported |
| Infrastructure Point of Contact Address |
Not Reported |
| Infrastructure Point of Contact City |
Not Reported |
| Infrastructure Point of Contact State |
Not Reported |
| Infrastructure Point of Contact Zip |
Not Reported |
Product or Service Information
(Grants)
| Product or Service Information |
| Primary Activity Code |
G01 |
| Activity Description |
Diseases, Disorders & Medical Disciplines, General/Other |
| Sub-Awards Information |
| Sub-awards to Organizations |
0 |
| Sub-award Amounts to Organizations |
$0 |
| Sub-Awards to Individuals |
0 |
| Sub-Award Amounts to Individuals |
$0 |
| Number of Sub-awards less than $25,000/award |
0 |
| Amount of Sub-awards less than $25,000/award |
$0 |
| Number of payments to vendors greater than $25,000 |
2 |
| Total Amount of payments to vendors greater than $25,000/award |
$1,188,608 |
| Number of payments to vendors less than $25,000/award |
0 |
| Total Amount of payments to vendors less than $25,000/award |
$0 |
Carl Zeiss Microimaging - Award Number 1S10RR029731-01 - Carl Zeiss Microimaging
| Award Number |
1S10RR029731-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
Not reported |
| Vendor HQ Zip Code + 4 |
10087-5943 |
| Vendor Name |
Carl Zeiss Microimaging |
| Product and Service Description |
LABORATORY & SCIENTIFIC FURNISHINGS & EQUIPMENT |
| Payment Amount |
$893,608 |
Coherent, Inc. - Award Number 1S10RR029731-01 - Coherent, Inc.
| Award Number |
1S10RR029731-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
043719210 |
| Vendor HQ Zip Code + 4 |
95054-1112 |
| Vendor Name |
Coherent, Inc. |
| Product and Service Description |
LABORATORY & SCIENTIFIC FURNISHINGS & EQUIPMENT |
| Payment Amount |
$295,000 |
| Location Information |
| Latitude, Longitude |
32º 48' 45",
-96º 50' 18" |
| Congressional District |
30 |
| Address 1 |
5323 Harry Hines |
| Address 2 |
|
| City |
Dallas |
| County |
Dallas |
| State |
TX |
| Zip |
75390-9020 |
|
 |