SCHEPENS EYE RESEARCH INSTITUTE, INC., THE
Studies described in this proposal seek to elucidate thrombospondin-1 (TSP-1) mediated immune regulation and associated mechanisms that may prevent ocular inflammaton. The first aim seeks to determine immunologic mechanisms underlying ocular inflammation in TSP-1null mice. The second aim seeks to investigate whether reconstitution of TSP-1 or peptides derived from this protein can resolve or prevent ocular inflammation. These studies will allow us to evaluate if any of the TSP-1 dependent mechanisms can form the basis for development of novel therapies to resolve chronic ocular inflammatory diseases.
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| AWARD OVERVIEW |
| Award Number |
2R01EY015472-06 |
Funding Agency |
Department of Health and Human Services |
| Total Award Amount |
$976,875 |
Project Location - City |
Boston |
| Award Date |
09/30/2009 |
Project Location - State |
MA |
| Project Status |
Completed |
Project Location - Zip |
02114-2500
|
| Jobs Reported |
3.00 |
Congressional District |
09 |
| Project Location - Country |
US |
|
|
Recipient Information
(Grants)
| Recipient Information (Grants) |
|
Recipient Name
|
SCHEPENS EYE RESEARCH INSTITUTE, INC., THE |
| Recipient DUNS Number |
073826000
|
| Recipient Address |
20 STANIFORD ST |
| Recipient City |
BOSTON |
| Recipient State |
Massachusetts |
| Recipient Zip |
02114-2508 |
| Recipient Congressional District |
09 |
| Recipient Country |
USA |
Required to Report Top 5
Highly Compensated Officials |
No |
Projects and Jobs Information
| Projects and Jobs Information |
| Project Title |
Thrombospondin-dependent mechanisms that regulate ocular inflammation. |
| Project Status |
Completed |
| Final Project Report Submitted |
Yes |
| Project Activities Description |
Eye Diseases, Blindness & Vision Impairments Research |
| Quarterly Activities/Project Description |
As defined in the Award Description field |
| Jobs Created |
3.00 |
| Description of Jobs Created |
(1) Principal Investigator (PI): A PI will oversee all aspects of this research project and related personnel, including experimental design, data interpretation and publication of the resulting data. (2) Research Associate (RA): An RA manages routine operations of the laboratory and also performs experiments independently that include cell cultures, in vitro assays in cellular immunology and biochemistry as well as flow cytometry and fluorescence microscopy. (3) Post-doctoral Fellow: A fellow in this position performs experiments independently, analyzes and interprets data for presentations in professional meetings and publications. The experimental design to address key questions in the project is prepared under the guidance of the PI. |
Purchaser Information
(Grants)
| Purchaser Information |
| Contracting Office ID |
Not Reported |
| Contracting Office Name |
Not Available |
| Contracting Office Region |
Not Available |
| TAS Major Program |
75-0902 |
| Award Information |
| Award Date |
09/30/2009 |
| Award Number |
2R01EY015472-06 |
| Order Number |
|
| Award Type |
Grants |
| Funding Agency ID |
75 |
| Funding Agency Name |
Department of Health and Human Services |
| Funding Office Name |
Not Available |
| Awarding Agency ID |
75 |
| Awarding Agency Name |
Department of Health and Human Services |
| Amount of Award |
$976,875 |
| Funds Invoiced/Received |
$976,875 |
| Expenditure Amount |
$976,875 |
| Infrastructure Expenditure Amount |
$0 |
| Infrastructure Purpose and Rationale |
Not Reported |
| Infrastructure Point of Contact Name |
Not Reported |
| Infrastructure Point of Contact Email |
Not Reported |
| Infrastructure Point of Contact Phone |
Not Reported |
| Infrastructure Point of Contact Address |
Not Reported |
| Infrastructure Point of Contact City |
Not Reported |
| Infrastructure Point of Contact State |
Not Reported |
| Infrastructure Point of Contact Zip |
Not Reported |
Product or Service Information
(Grants)
| Product or Service Information |
| Primary Activity Code |
H02.11 |
| Activity Description |
Eye Diseases, Blindness & Vision Impairments Research |
| Sub-Awards Information |
| Sub-awards to Organizations |
0 |
| Sub-award Amounts to Organizations |
$0 |
| Sub-Awards to Individuals |
0 |
| Sub-Award Amounts to Individuals |
$0 |
| Number of Sub-awards less than $25,000/award |
0 |
| Amount of Sub-awards less than $25,000/award |
$0 |
| Number of payments to vendors greater than $25,000 |
0 |
| Total Amount of payments to vendors greater than $25,000/award |
$0 |
| Number of payments to vendors less than $25,000/award |
0 |
| Total Amount of payments to vendors less than $25,000/award |
$0 |
| Location Information |
| Latitude, Longitude |
42º 21' 43",
-71º 3' 50" |
| Congressional District |
09 |
| Address 1 |
20 Staniford Street |
| Address 2 |
|
| City |
Boston |
| County |
Suffolk |
| State |
MA |
| Zip |
02114-2500 |
|
 |