Grants - AWARD SUMMARY


UNIVERSITY OF MASSACHUSETTS


The parent RO1 grant of this ARRA supplement received a score of 115 (1.3%) in 2007. The goal was to use both cultured rodent primary neurons and Drosophila models to examine molecular mechanisms of the pathogenesis of frontotemporal dementia (FTD). In this supplement supported by ARRA, we proposed to accelerate the tempo of this line of research and expect to clone 3 to5 genes that modulate the neurotoxicity of the FTD3 mutant protein CHMP2BIntron5 and (2) to characterize 1 to 2 genes and their related genetic pathways in detail..

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AWARD OVERVIEW

AWARD OVERVIEW
Award Number 3R01NS057553-04S1 Funding Agency Department of Health and Human Services
Total Award Amount $247,634 Project Location - City Worcester
Award Date 09/10/2010 Project Location - State MA
Project Status Completed Project Location - Zip 01655-0002
Jobs Reported 0.00 Congressional District 03
Project Location - Country US

Recipient Information (Grants)

Recipient Information (Grants)
Recipient Name UNIVERSITY OF MASSACHUSETTS
Recipient DUNS Number 603847393
Recipient Address 55 LAKE AVE N
Recipient City WORCESTER
Recipient State Massachusetts
Recipient Zip 01655-0002
Recipient Congressional District 03
Recipient Country USA
Required to Report Top 5
Highly Compensated Officials		 No

Projects and Jobs Information

Projects and Jobs Information
Project Title ARRA: Animal Models for Studying Human Frontotemporal Dementia
Project Status Completed
Final Project Report Submitted Yes
Project Activities Description Medical Research, General/Other
Quarterly Activities/Project Description During this quarter, we continued to perform a number of molecular and cellualr experiments to understand the mechanism by which the modifier gene affects the toxocity of mutant CHMP2B implicated in FTD3. We are finally in the position to write up this piece of work and expect to submit the mansucript sometime this summer or fall. The final invoicing for the project will be complete in the next couple weeks.
Jobs Created 0.00
Description of Jobs Created No jobs were funded by this project in the current quarter


Purchaser Information (Grants)

Purchaser Information
Contracting Office ID Not Reported
Contracting Office Name Not Available
Contracting Office Region Not Available
TAS Major Program 75-0901

Award Information

Award Information
Award Date 09/10/2010
Award Number 3R01NS057553-04S1
Order Number
Award Type Grants
Funding Agency ID 75
Funding Agency Name Department of Health and Human Services
Funding Office Name Not Available
Awarding Agency ID 75
Awarding Agency Name Department of Health and Human Services
Amount of Award $247,634
Funds Invoiced/Received $247,631
Expenditure Amount $247,634
Infrastructure Expenditure Amount $0
Infrastructure Purpose and Rationale Not Reported
Infrastructure Point of Contact Name Not Reported
Infrastructure Point of Contact Email Not Reported
Infrastructure Point of Contact Phone Not Reported
Infrastructure Point of Contact Address Not Reported
Infrastructure Point of Contact City Not Reported
Infrastructure Point of Contact State Not Reported
Infrastructure Point of Contact Zip Not Reported

Product or Service Information (Grants)

Product or Service Information
Primary Activity Code H01
Activity Description Medical Research, General/Other

Sub-Awards Information

Sub-Awards Information
Sub-awards to Organizations 0
Sub-award Amounts to Organizations $0
Sub-Awards to Individuals 0
Sub-Award Amounts to Individuals $0
Number of Sub-awards less than $25,000/award 0
Amount of Sub-awards less than $25,000/award $0
Number of payments to vendors greater than $25,000 0
Total Amount of payments to vendors greater than $25,000/award $0
Number of payments to vendors less than $25,000/award 327
Total Amount of payments to vendors less than $25,000/award $87,584







Project Location Detail

Location Information
Latitude, Longitude 42º 16' 39", -71º 45' 33"
Congressional District 03
Address 1 55 Lake Avenue North
Address 2
City Worcester
County Worcester
State MA
Zip 01655-0002
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