UNIVERSITY OF WASHINGTON
The objective of the project is to accelerate collaboration and a new model for multidisciplinary interaction across cognitive neuroscience, human neuroimaging and medicine at the University of Washington. The project specifically uses the infrastructure of the Integrated Brain Imaging Center to partner with existing established Centers and groups whose scientific programs call for immediate imaging expertise to investigate basic and translational areas in neurodegenerative disease, brain aging, epilepsy, and rehabilitation of paralysis. The proposed project will launch two interacting project clusters. The first clusterexploits multimodal imaging methods, advanced MR spectroscopy, and a neural systems perspective to advance understanding of pathophysiology of incipient Azheimer disease and aging, the basis of variable cognitive impairment in Parkinson disease, factors governing cognitive prognosis in epilepsy surgery, and the neural bases of successful cognitive aging. These groups include the Pacific Northwest Udall Center for the study of cognition in Parkinson disease, the Northwest Research Group on Aging, the Seattle Longitudinal Study, the Translational Center for in vivo Mitochondrial Medicine, and the Neuroimaging & Biotechnology Laboratory. The second cluster is driven by outstanding UW expertise in human neurophysiology, electrophysiology and sensorimotor engineering, and focuses on integration of systems neuroimaging approaches and human electrophysiology, to advance methodology for delineating neural systems in vivo, to understand the dynamics of clinically relevant large scale systems (default mode network, dorsal attentional network) and to improve the extraction of motor signals for rehabilitationof paralysis. These groups include the University of Washington Regional Epilepsy Center, and the UW Center for Sensorimotor Neural Engineering. These interdisciplinary projects will be supplemented by simultaneous technical developments in IBIC: 1) implementation of simultaneous EEG-fMRI, 2) advancing systems neuroimaging with diffusion-based cortical parcellation and novel applications of functional connectivity of spontaneous activity ("resting state") fMRI and pattern analysis fMRI; and 3) expansion of IVAN (Interoperable and Virtualized Analysis for Neuroimaging) a project that implements analysis pipelines of open source tools with virtualization and is aligned with ongoing multicenter efforts (NIPy, NIPype). The impact of these new relationships is illustrated by specific studies that draw on members of multiple groups, but the full impact of the project will lie in the consolidation of a long-overdue campuswide research resource for a major biomedical research center, carrying the potential to advance neuroscience across a broad front.
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| AWARD OVERVIEW |
| Award Number |
1RC4NS073008-01 |
Funding Agency |
Department of Health and Human Services |
| Total Award Amount |
$4,784,830 |
Project Location - City |
SEATTLE |
| Award Date |
09/28/2010 |
Project Location - State |
WA |
| Project Status |
More than 50% Completed |
Project Location - Zip |
98195-0000
|
| Jobs Reported |
15.87 |
Congressional District |
07 |
| Project Location - Country |
US |
|
|
Recipient Information
(Grants)
| Recipient Information (Grants) |
|
Recipient Name
|
UNIVERSITY OF WASHINGTON |
| Recipient DUNS Number |
605799469
|
| Recipient Address |
4333 BROOKLYN AVE NE |
| Recipient City |
SEATTLE |
| Recipient State |
Washington |
| Recipient Zip |
98195-0001 |
| Recipient Congressional District |
07 |
| Recipient Country |
USA |
Required to Report Top 5
Highly Compensated Officials |
No |
Projects and Jobs Information
| Projects and Jobs Information |
| Project Title |
IBIC: Integrated Brain Imaging Center for the University of Washington |
| Project Status |
More than 50% Completed |
| Final Project Report Submitted |
No |
| Project Activities Description |
Medical Research, General/Other |
| Quarterly Activities/Project Description |
We enrolled an additional 12 subjects in the fcMRI study of cholinergic responsiveness in Parkinson disease. We submitted initial functional connectivity analysis to OHBM 2013. (Project 1). We enrolled 10 additional MCI subjects in the MRS and imaging study. We advanced development of single- and dual-tuned 3T P-coils to stage of safety testing (Projects 2 and 3). We continued analysis of fcMRI data in aging, where data collection is complete (Project 4) We began collecting data on control subjects for pattern-analysis studies of semantic organization in the temporal lobes (Project 5). We continued development of quality metrics for diffusion-based cortical parcellation (Project 6). In the brain-computer interface project, 4 additional subjects were scanned with the specialized FLASH and MEMPRAGE sequences that facilitate automated head model generation, and we recorded EEG data offline from 8 subjects using a motor imagery paradigm. We submitted preliminary analysis to OHBM 2013 (Project 7). We have made progress in quality control workflow and provenance models for resting state fMRI data (Data sharing plan). |
| Jobs Created |
15.87 |
| Description of Jobs Created |
ACTING ASSISTANT PROFESSOR-TEMP-Requires a demonstration of teaching and research ability beyond that ordinarily required of an instructor. ACTING INSTRUCTOR-Normally requires completion of professional training, in many fields marked by the Ph.D. and the promise of a successful career in teaching and research. ASSOCIATE PROFESSOR-Requires a record of substantial success in both teaching and research, except that in unusual cases an outstanding record in one of these activities may be considered sufficient. ASST PROFESSOR WITHOUT TENURE-Requires a demonstration of teaching and research ability beyond that ordinarily required of an instructor. Faculty members WOT are funded by a variety of sources with a focus on research activities. OFFICE ASSISTANT 1-Copy materials, file documents, post records, answer telephones. PHYS ASST-ADV RN PRACTITIONER-Provide medical care to patients under the guidance of an attending physician; performing examinations, establishing diagnoses and determining appropriate treatment or referral for medical problems. PREDOCTORAL RESEARCH ASSOCIATE 1-Engage in research on sponsored projects under general supv of faculty/research staff. PREDOCTORAL RESEARCH ASSOCIATE 2-Engage in research on sponsored projects under general supv of faculty/research staff. PROFESSOR WITHOUT TENURE-Requires outstanding, mature scholarship and research as evaluated in terms of national or international recognition, and evidenced by accomplishments in full range of academic responsibilities. PROGRAM OPERATIONS SPECIALIST-Provide direction and control of a defined program, accountable for allocation of resources and program results. PROJECT APPOINTMENT - OVERTIME EXEMPT-Perform assigned professional work. RESEARCH ASSISTANT PROFESSOR-Requires a demonstration of teaching and research ability beyond that ordinarily required of an instructor. RESEARCH ASSISTANT-Engage in research on sponsored projects under general supv of faculty/research staff. May include independent research under the guidance of a faculty member. Normally a pre-masters student. RESEARCH ASSOC PROF EMERITUS-Requires outstanding, mature scholarship and research as evaluated in terms of national or international recognition, and evidenced by accomplishments in full range of academic responsibilities. RESEARCH COORDINATOR-Provide coordination for significant multi-funded or multi-site research project(s). Participate in development of research designs; methods and strategies for data management and collection. RESEARCH COORDINATOR-Under dir. of a PI, provide overall coord of a research project. RESEARCH PROFESSOR-Requires outstanding, mature scholarship and research as evaluated in terms of national or international recognition, and evidenced by accomplishments in full range of academic responsibilities. RESEARCH SCIENTIST/ENGINEER 3-Independently select and apply techniques or procedures to assignments of moderate complexity, potentially involving conflicting design requirements, unavailability of materials or resources. RESEARCH SCIENTIST/ENGINEER 4-Make ind. judgments re: appl of scientific techniques/procedures. RESEARCH STUDY ASSISTANT-Perform varied support functions in support of research studies involving human subjects. RESEARCH STUDY COORDINATOR 1-Coordinate the operations of clinical, biomedical and/or behavioral research studies involving human subjects. RESEARCH TECHNOLOGIST 1-Perform technical procedures and operate analytical instruments in support of investigative procedures in a scientific research setting. SENIOR COMPUTER SPECIALIST-Provide technical expertise in complex aspects of computing technology. Requires high level of knowledge of hardware and software technologies. Develop complex web, database and software applications. SENIOR FELLOW-Works under the direction of PI for the benefit of the research programs, the departments educational program, and their own professional growth. |
Purchaser Information
(Grants)
| Purchaser Information |
| Contracting Office ID |
Not Reported |
| Contracting Office Name |
Not Available |
| Contracting Office Region |
Not Available |
| TAS Major Program |
75-0901 |
| Award Information |
| Award Date |
09/28/2010 |
| Award Number |
1RC4NS073008-01 |
| Order Number |
|
| Award Type |
Grants |
| Funding Agency ID |
75 |
| Funding Agency Name |
Department of Health and Human Services |
| Funding Office Name |
Not Available |
| Awarding Agency ID |
75 |
| Awarding Agency Name |
Department of Health and Human Services |
| Amount of Award |
$4,784,830 |
| Funds Invoiced/Received |
$3,743,711 |
| Expenditure Amount |
$3,766,803 |
| Infrastructure Expenditure Amount |
$0 |
| Infrastructure Purpose and Rationale |
Not Reported |
| Infrastructure Point of Contact Name |
Not Reported |
| Infrastructure Point of Contact Email |
Not Reported |
| Infrastructure Point of Contact Phone |
Not Reported |
| Infrastructure Point of Contact Address |
Not Reported |
| Infrastructure Point of Contact City |
Not Reported |
| Infrastructure Point of Contact State |
Not Reported |
| Infrastructure Point of Contact Zip |
Not Reported |
Product or Service Information
(Grants)
| Product or Service Information |
| Primary Activity Code |
H01 |
| Activity Description |
Medical Research, General/Other |
| Sub-Awards Information |
| Sub-awards to Organizations |
1 |
| Sub-award Amounts to Organizations |
$48,972 |
| Sub-Awards to Individuals |
0 |
| Sub-Award Amounts to Individuals |
$0 |
| Number of Sub-awards less than $25,000/award |
0 |
| Amount of Sub-awards less than $25,000/award |
$0 |
| Number of payments to vendors greater than $25,000 |
1 |
| Total Amount of payments to vendors greater than $25,000/award |
$29,075 |
| Number of payments to vendors less than $25,000/award |
46 |
| Total Amount of payments to vendors less than $25,000/award |
$117,297 |
Sub-award 728386Z - SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH
| Sub-Award Amount |
$48,972 |
| Sub-Award Date |
10/28/2011 |
| Sub-Awards Disbursed |
$30,862.80 |
| Project Location - City |
SEATTLE |
| Project Location - State |
WA |
| Project Location - Zip Code |
98108-1532 |
| Project Location - Congressional District |
09 |
| Sub-Recipient DUNS Number |
928470061
|
| Sub-Recipient Address |
1660 S COLUMBIAN WAY # 151F |
| Sub-Recipient City |
SEATTLE |
| Sub-Recipient State |
Washington |
| Sub-Recipient Zip Code |
98108-1532 |
| Sub-Recipient Congressional District |
09 |
Required To Report Top 5
Highly Compensated Officials |
No |
ELECTRICAL GEODESICS, INC. - Award Number 1RC4NS073008-01 - ELECTRICAL GEODESICS, INC.
| Award Number |
1RC4NS073008-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
809845365 |
| Vendor HQ Zip Code + 4 |
97403-1995 |
| Vendor Name |
ELECTRICAL GEODESICS, INC. |
| Product and Service Description |
128 CHANNEL PORTABLE GEODESIC EEG SYSTEM 300 ITEM |
| Payment Amount |
$29,075 |
| Location Information |
| Latitude, Longitude |
47º 39' 17",
-122º 18' 7" |
| Congressional District |
07 |
| Address 1 |
4333 Brooklyn Avenue, NE |
| Address 2 |
|
| City |
SEATTLE |
| County |
King |
| State |
WA |
| Zip |
98195-0000 |
|
 |