NATIONAL JEWISH HEALTH
The overall purpose of the project funded by this award is to support the early independent phase of the career of a pulmonary physician-scientist at National Jewish Health. National Jewish Health is the world's only institution that is dedicated to the treatment and research of pulmonary and immune-mediated disease. To further the overall mission of National Jewish Health, a physician-scientist was recruited to join the Pulmonary Division and the Airway Biology Core at National Jewish Health and to establish his own laboratory that researches glucocorticoid receptor signaling in airway cells. This award will allow the newly recruited investigator to establish a state-of-the art laboratory for the analysis of gene regulation in the airway, and to hire several highly skilled researchers to conduct research on airway gene regulation. Specifically, the award will help provide the newly recruited investigator with protected time to conduct research, it will allow for the purchase of key equipment required to successfully run a molecular biology laboratory, it will provide for the employment of several research associates, and will provide money to support day-to-day laboratory operations. It is anticipated that this award will lead to both publications and the award of additional peer reviewed grants. These items will be tracked during and after the award period. It is also anticipated that the award will facilitate collaborations between different scientists at National Jewish, as indicated by joint projects, publications, and research awards.
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| AWARD OVERVIEW |
| Award Number |
1P30HL101294-01 |
Funding Agency |
Department of Health and Human Services |
| Total Award Amount |
$1,352,937 |
Project Location - City |
Denver |
| Award Date |
09/18/2009 |
Project Location - State |
CO |
| Project Status |
Completed |
Project Location - Zip |
80206-2761
|
| Jobs Reported |
0.00 |
Congressional District |
01 |
| Project Location - Country |
US |
|
|
Recipient Information
(Grants)
| Recipient Information (Grants) |
|
Recipient Name
|
NATIONAL JEWISH HEALTH |
| Recipient DUNS Number |
076443019
|
| Recipient Address |
1400 JACKSON ST |
| Recipient City |
DENVER |
| Recipient State |
Colorado |
| Recipient Zip |
80206-2761 |
| Recipient Congressional District |
01 |
| Recipient Country |
USA |
Required to Report Top 5
Highly Compensated Officials |
No |
Projects and Jobs Information
| Projects and Jobs Information |
| Project Title |
Fostering Collaborations and the Career of a Newly Recruited Pulmonary Scientist |
| Project Status |
Completed |
| Final Project Report Submitted |
Yes |
| Project Activities Description |
Medical Research, General/Other |
| Quarterly Activities/Project Description |
The overall purpose of this award is to support the career of a newly independent physician scientist. The first element of the award was to support the successful transition of the newly recruited investigator into the research environment at National Jewish Health (NJH). This process has been completed. The PI supported by the award has fully equipped his laboratory, and the laboratory is running effectively with 4 staff members. During the last quarter, the supported investigator began utlizing funds from an RO1 award and tarnsitioned off of the ARRA grant. During the last quarter, the PI presented his work in an oral presentation at a FASEB meeting in Snowmass, CO. A manuscript on Klf15 and GR was also prepared fro submisssion. |
| Jobs Created |
0.00 |
| Description of Jobs Created |
From July 1, 2010 to August 31, 2011, the salary for the newly recruited physician scientist was substantially supported by this award, allowing him to have a large percentage of time devoted to cutting edge scientific research on asthma biology and therapy, an illness that afflicts millions of Americans. Since August 31, 2011, as a component of the award, the supported investigator is now supported by a combination of institutional funds and clinical work, with a total of 75% time protected for research. His protected research time has allowed him to supervise a total of six additional scientists, all of whose jobs were created with funds provided by this award, or through institutional support that was guaranteed as part of the award application. At this juncture, the newly recruited investigator supervises three Ph.D level biology researchers whose psoitions were initially created with funds from this award. One began work on 11/30/09 and the other on 6/1/10. Two of these scientists recieved their Ph.D. degrees at prestigious universities in the USA, and the funds from this award have allowed them to continue their sceintific careers. These researchers are working on the molecular mechanism of glucocorticoid action in airway cells. Both post-doctoral scientists are receiving specialized training in lung biology and transcriptional regulation while conducting the research projects in the laboratory of the new investigator. This training has enabled one of the post-doctoral sceintists to obtain a position asa an assistnat lab director for a small company doing personalized laboratory medicine. Thus, these funds led directly to a trainee receiving a position in the private sector. Moreover, a third post-doctoral associate was recently hired, using institutional funds provided to the PI as part of the P30 award. In addition, a full time lab researcher was hired January, 2012. Her support is also based on institutional funds that were provided to the PI as part of the P30 award. It is anticipated that this Lab Researcher will be funded in the future using funds from an RO1 award, which was written based on work accomplished with funds from the P30. In addition, the PI previously employed another Lab Researcher II who was supported for ~ 1 year with ARRA funds. She obtained a new job at UC Denver in January 2011 where she is using skills acquired during her time of support with ARRA funds. A part-time researcher (32 hrs a week) was hired at 50% effort in February 2010, and transitioned to 80% effort from July 15, 2010 to December 1st, 2010. The part-time researcher assisted the post-doctoral scientists, and received specialized trained in a variety of molecular techniques. Her position was subsequently eliminated, however, she was able to obtain another full time position at National Jewish Health. The post-doctoral positions continue to be supported by funds from this award. As the supported investigator now receives funding throuygh an R01 award, it is anticipated that two post-doctoral positions will continue through at least 8/31/2015. Following their period of employment by National Jewish Health, the Ph.D. level scientists will be highly trained and able to continue to work in an academic setting or obtain scientist level positions in Biotechnology, a key growth sector in the economy. If the research career of the newly recruited scientist continues to flourish it is anticipated that there will be a total of 4 long-term jobs, including his own, that arose directly from this award. |
Purchaser Information
(Grants)
| Purchaser Information |
| Contracting Office ID |
Not Reported |
| Contracting Office Name |
Not Available |
| Contracting Office Region |
Not Available |
| TAS Major Program |
75-0871 |
| Award Information |
| Award Date |
09/18/2009 |
| Award Number |
1P30HL101294-01 |
| Order Number |
|
| Award Type |
Grants |
| Funding Agency ID |
75 |
| Funding Agency Name |
Department of Health and Human Services |
| Funding Office Name |
Not Available |
| Awarding Agency ID |
75 |
| Awarding Agency Name |
Department of Health and Human Services |
| Amount of Award |
$1,352,937 |
| Funds Invoiced/Received |
$1,352,937 |
| Expenditure Amount |
$1,352,937 |
| Infrastructure Expenditure Amount |
$0 |
| Infrastructure Purpose and Rationale |
N/A |
| Infrastructure Point of Contact Name |
N/A |
| Infrastructure Point of Contact Email |
Not Reported |
| Infrastructure Point of Contact Phone |
Not Reported |
| Infrastructure Point of Contact Address |
Not Reported |
| Infrastructure Point of Contact City |
Not Reported |
| Infrastructure Point of Contact State |
Not Reported |
| Infrastructure Point of Contact Zip |
Not Reported |
Product or Service Information
(Grants)
| Product or Service Information |
| Primary Activity Code |
H01 |
| Activity Description |
Medical Research, General/Other |
| Sub-Awards Information |
| Sub-awards to Organizations |
0 |
| Sub-award Amounts to Organizations |
$0 |
| Sub-Awards to Individuals |
0 |
| Sub-Award Amounts to Individuals |
$0 |
| Number of Sub-awards less than $25,000/award |
0 |
| Amount of Sub-awards less than $25,000/award |
$0 |
| Number of payments to vendors greater than $25,000 |
4 |
| Total Amount of payments to vendors greater than $25,000/award |
$134,008 |
| Number of payments to vendors less than $25,000/award |
427 |
| Total Amount of payments to vendors less than $25,000/award |
$321,167 |
APPLIED BIOSYSTEMS - Award Number 1P30HL101294-01 - APPLIED BIOSYSTEMS
| Award Number |
1P30HL101294-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
Not reported |
| Vendor HQ Zip Code + 4 |
60695-1976 |
| Vendor Name |
APPLIED BIOSYSTEMS |
| Product and Service Description |
Stepone Plus 96 Well Rt PCR System Tower |
| Payment Amount |
$35,500 |
Carl Zeiss Microimaging - Award Number 1P30HL101294-01 - Carl Zeiss Microimaging
| Award Number |
1P30HL101294-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
Not reported |
| Vendor HQ Zip Code + 4 |
10594-1939 |
| Vendor Name |
Carl Zeiss Microimaging |
| Product and Service Description |
Axio Observer A1 Microscope |
| Payment Amount |
$29,006 |
Jackson Laboratory - Award Number 1P30HL101294-01 - Jackson Laboratory
| Award Number |
1P30HL101294-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
Not reported |
| Vendor HQ Zip Code + 4 |
04609-1523 |
| Vendor Name |
Jackson Laboratory |
| Product and Service Description |
Genetics Research Lab, Providing Services and Resources |
| Payment Amount |
$25,267 |
Tecan US Inc - Award Number 1P30HL101294-01 - Tecan US Inc
| Award Number |
1P30HL101294-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
Not reported |
| Vendor HQ Zip Code + 4 |
27709-1070 |
| Vendor Name |
Tecan US Inc |
| Product and Service Description |
Monochromator - Excitation/Emission/Fluroescence |
| Payment Amount |
$44,235 |
| Location Information |
| Latitude, Longitude |
39º 44' 21",
-104º 56' 34" |
| Congressional District |
01 |
| Address 1 |
1400 Jackson Street |
| Address 2 |
|
| City |
Denver |
| County |
Denver |
| State |
CO |
| Zip |
80206-2761 |
|
 |