UNIVERSITY OF KENTUCKY
T.his is a NIH P30 Biomedical Research Core Center Application (RFA-OD-09-005) on Fetal Programming in the Development of Obesity-induced Cardiovascular Diseases. The request is for support of salary and start-up costs for recruit of one new investigator for appointment within the Graduate Center for Nutritional Sciences (GCNS), a multidisciplinary research and graduate program within the College of Medicine. The research area of fetal programming through dietary manipulation as a mechanism promoting obesity and cardiovascular disease in adult offspring will complement and extend an NIH funded Center of Biomedical Research Excellence (COBRE) on obesity and cardiovascular diseases. Specialized research cores, extensive University Core Facilities, and established mentoring mechanisms are in place to promote development of an independent research program towards R01 competitiveness within the research area. The new faculty recruit will be assigned dedicated research space within the highly collaborative environment of the GCNS, with availability to common use equipment and specialized cores for analytical measurements, tissue pathology, radiotelemetry measurement of blood pressure, and whole body metabolism in mice. The targeted research area complements and extends studies currently focused on identification of mechanisms linking diet-induced obesity in adults in the development of cardiovascular disease. In this sister P30 Center, new faculty recruits will examine effects of fetal programming through dietary manipulation during pregnancy on the development of obesity and cardiovascular diseases in adult offspring. Given the increasing prevalence of obesity in the US, it is important to identify the impact of maternal obesity, through consumption of a western diet, on disease development in offspring. Moreover, these sister Centers span the breadth of current research by contrasting effects of obesity during development from adult onset obesity-induced cardiovascular disease. We will use our existing strengths in mentoring and our focused research cores within the defined area of study to assure that new investigators develop independent research programs of clinical significance to the missions of NIH HLBI.
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| AWARD OVERVIEW |
| Award Number |
1P30HL101300-01 |
Funding Agency |
Department of Health and Human Services |
| Total Award Amount |
$1,110,233 |
Project Location - City |
Lexington |
| Award Date |
09/30/2009 |
Project Location - State |
KY |
| Project Status |
More than 50% Completed |
Project Location - Zip |
40508-0000
|
| Jobs Reported |
0.75 |
Congressional District |
06 |
| Project Location - Country |
US |
|
|
Recipient Information
(Grants)
| Recipient Information (Grants) |
|
Recipient Name
|
UNIVERSITY OF KENTUCKY |
| Recipient DUNS Number |
939017877
|
| Recipient Address |
500 S LIMESTONE 109 KINKEAD HALL |
| Recipient City |
LEXINGTON |
| Recipient State |
Kentucky |
| Recipient Zip |
40526-0001 |
| Recipient Congressional District |
06 |
| Recipient Country |
USA |
Required to Report Top 5 Highly Compensated Officials |
No |
Projects and Jobs Information
| Projects and Jobs Information |
| Project Title |
Biomedical Research Core Center (P30) on Fetal Programming |
| Project Status |
More than 50% Completed |
| Final Project Report Submitted |
No |
| Project Activities Description |
Cardiovascular Diseases Research |
| Quarterly Activities/Project Description |
We have hired one Assistant Professor within the Graduate Center for Nutritional Sciences. The impact of this hire is tremendous, as the new faculty position will contribute to the diverse missions of teaching, research and service that are significant for this small educational unit. The recruited faculty member brings a new dimension of research to the center in the area of fetal programming and cardiovascular disease, and in definition of fundamental processes important in the development of obesity, diabetes, and atherosclerosis. The new faculty member has filled two laboratory positions necessary to implement the proposed research, a laboratory technician a post-doctoral fellow, and a temporary research scientist. Technical staff and post-doctoral fellows have been interviewed and hired for these positions. The addition of these staff to the workforce will expand current research capabilities by providing new technical skills and through new equipment available to the workplace. |
| Jobs Created |
0.75 |
| Description of Jobs Created |
We have hired one Assistant Professor (0.25 FTE) within the Graduate Center for Nutritional Sciences. The impact of this hire is tremendous, as the new faculty position will contribute to the diverse missions of teaching, research and service that are significant for this small educational unit. The recruited faculty member brings a new dimension of research to the center in the area of fetal programming and cardiovascular disease, and in definition of fundamental processes important in the development of obesity, diabetes, and atherosclerosis. The new faculty member will fill laboratory positions necessary to implement the proposed research: one Post-Doctoral Scholar (0.50 FTE). The addition of these staff to the workforce will expand current research capabilities by providing new technical skills and through new equipment available to the workplace. |
Purchaser Information
(Grants)
| Purchaser Information |
| Contracting Office ID |
Not Reported |
| Contracting Office Name |
Not Available |
| Contracting Office Region |
Not Available |
| TAS Major Program |
75-0871 |
| Award Information |
| Award Date |
09/30/2009 |
| Award Number |
1P30HL101300-01 |
| Order Number |
|
| Award Type |
Grants |
| Funding Agency ID |
75 |
| Funding Agency Name |
Department of Health and Human Services |
| Funding Office Name |
Not Available |
| Awarding Agency ID |
75 |
| Awarding Agency Name |
Department of Health and Human Services |
| Amount of Award |
$1,110,233 |
| Funds Invoiced/Received |
$1,094,517 |
| Expenditure Amount |
$1,094,517 |
| Infrastructure Expenditure Amount |
$0 |
| Infrastructure Purpose and Rationale |
Not Reported |
| Infrastructure Point of Contact Name |
Not Reported |
| Infrastructure Point of Contact Email |
Not Reported |
| Infrastructure Point of Contact Phone |
Not Reported |
| Infrastructure Point of Contact Address |
Not Reported |
| Infrastructure Point of Contact City |
Not Reported |
| Infrastructure Point of Contact State |
Not Reported |
| Infrastructure Point of Contact Zip |
Not Reported |
Product or Service Information
(Grants)
| Product or Service Information |
| Primary Activity Code |
H02.05 |
| Activity Description |
Cardiovascular Diseases Research |
| Sub-Awards Information |
| Sub-awards to Organizations |
0 |
| Sub-award Amounts to Organizations |
$0 |
| Sub-Awards to Individuals |
0 |
| Sub-Award Amounts to Individuals |
$0 |
| Number of Sub-awards less than $25,000/award |
0 |
| Amount of Sub-awards less than $25,000/award |
$0 |
| Number of payments to vendors greater than $25,000 |
2 |
| Total Amount of payments to vendors greater than $25,000/award |
$62,548 |
| Number of payments to vendors less than $25,000/award |
510 |
| Total Amount of payments to vendors less than $25,000/award |
$282,652 |
Bio-RAD Laboratories, Inc - Award Number 1P30HL101300-01 - Bio-RAD Laboratories, Inc
| Award Number |
1P30HL101300-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
884513334 |
| Vendor HQ Zip Code + 4 |
94547-1803 |
| Vendor Name |
Bio-RAD Laboratories, Inc |
| Product and Service Description |
Laboratory and Scientific Equipment |
| Payment Amount |
$29,981 |
BIOTEK INSTRUMENTS, INC. - Award Number 1P30HL101300-01 - BIOTEK INSTRUMENTS, INC.
| Award Number |
1P30HL101300-01 |
| Sub-Award Number |
N/A |
| Vendor DUNS Number |
049321599 |
| Vendor HQ Zip Code + 4 |
05404-1356 |
| Vendor Name |
BIOTEK INSTRUMENTS, INC. |
| Product and Service Description |
Laboratory and Scientific Equipment |
| Payment Amount |
$32,568 |
| Location Information |
| Latitude, Longitude |
38º 2' 12",
-84º 29' 57" |
| Congressional District |
06 |
| Address 1 |
109 Kinkead Hall |
| Address 2 |
|
| City |
Lexington |
| County |
Fayette |
| State |
KY |
| Zip |
40508-0000 |
|
 |