Grants - AWARD SUMMARY


KAISER FOUNDATION HOSPITALS


The goal of this "Grand Opportunities" project is to create a unique and comprehensive population-based resource for research into the genetic and environmental basis of common age-related diseases and their treatment, and factors influencing healthy aging and longevity. The proposed resource will bring together into a broadly accessible database, an extraordinarily rich set of data on 100,000 participants in the Research Program on Genes, Environment and Health (RPGEH), based in the Kaiser Permanente Medical Care Plan in Northern California (KPNC). The RPGEH includes data from the comprehensive, longitudinal electronic medical records of KPNC; a participant questionnaire with demographic, behavioral, and other risk factor data; a geographic information system (GIS) database that maps environmental exposures (e.g., air and water quality) and neighborhood characteristics to participants' residential histories; and saliva samples obtained from all participants using Oragene kits. The 100,000 completed participants in RPGEH have broadly consented to have their DNA and other data used to conduct studies of genetic and environmental influences on health and disease. The average age of the subjects is 65 years, with good representation of all the major ethnic groups. In this proposal, we are specifically requesting funds to add valuable genome-wide association data for 700,000 SNPs to the resource using a novel Affymetrix GeneTitan genotyping system, to enable comprehensive studies of genetic and environmental factors that influence the risk of adult-onset diseases and their treatment, and healthy aging. The selection of SNPs will be customized to facilitate the detection of new associations and to follow up previously identified associations. The longitudinal nature of the electronic clinical records maintained by KPNC means that the phenotype data subject to analysis can be used to address questions of health and disease over time. We anticipate that this resource will serve the needs of a vast array of researchers both nationally and internationally to investigate complex questions regarding aging, both for the short term and for years to come.

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AWARD OVERVIEW

AWARD OVERVIEW
Award Number 1RC2AG036607-01 Funding Agency Department of Health and Human Services
Total Award Amount $24,846,000 Project Location - City Oakland
Award Date 09/29/2009 Project Location - State CA
Project Status More than 50% Completed Project Location - Zip 94612-2304
Jobs Reported 0.00 Congressional District 13
Project Location - Country US

Recipient Information (Grants)

Recipient Information (Grants)
Recipient Name KAISER FOUNDATION HOSPITALS
Recipient DUNS Number 150829349
Recipient Address 1800 HARRISON ST FL 16
Recipient City OAKLAND
Recipient State California
Recipient Zip 94612-3429
Recipient Congressional District 13
Recipient Country USA
Required to Report Top 5
Highly Compensated Officials
No

Projects and Jobs Information

Projects and Jobs Information
Project Title A Resource for Genetic Epidemiology Research in Adult Health and Aging
Project Status More than 50% Completed
Final Project Report Submitted No
Project Activities Description Diseases & Disorders Research
Quarterly Activities/Project Description As defined in the Award Description.
Jobs Created 0.00
Description of Jobs Created Positions of jobs created/retained:


Purchaser Information (Grants)

Purchaser Information
Contracting Office ID Not Reported
Contracting Office Name Not Available
Contracting Office Region Not Available
TAS Major Program 75-0842

Award Information

Award Information
Award Date 09/29/2009
Award Number 1RC2AG036607-01
Order Number
Award Type Grants
Funding Agency ID 75
Funding Agency Name Department of Health and Human Services
Funding Office Name Not Available
Awarding Agency ID 75
Awarding Agency Name Department of Health and Human Services
Amount of Award $24,846,000
Funds Invoiced/Received $24,845,999
Expenditure Amount $24,845,999
Infrastructure Expenditure Amount $0
Infrastructure Purpose and Rationale Not Reported
Infrastructure Point of Contact Name Not Reported
Infrastructure Point of Contact Email Not Reported
Infrastructure Point of Contact Phone Not Reported
Infrastructure Point of Contact Address Not Reported
Infrastructure Point of Contact City Not Reported
Infrastructure Point of Contact State Not Reported
Infrastructure Point of Contact Zip Not Reported

Product or Service Information (Grants)

Product or Service Information
Primary Activity Code H02
Activity Description Diseases & Disorders Research

Sub-Awards Information

Sub-Awards Information
Sub-awards to Organizations 2
Sub-award Amounts to Organizations $8,029,299
Sub-Awards to Individuals 0
Sub-Award Amounts to Individuals $0
Number of Sub-awards less than $25,000/award 0
Amount of Sub-awards less than $25,000/award $0
Number of payments to vendors greater than $25,000 20
Total Amount of payments to vendors greater than $25,000/award $15,049,729
Number of payments to vendors less than $25,000/award 45
Total Amount of payments to vendors less than $25,000/award $161,132


Sub-Award Transactions

Sub-award CN-09CScha06-H (15-9766-02) - LELAND STANFORD JUNIOR UNIVERSITY, THE

Sub-Award Amount $199,019
Sub-Award Date 03/13/2012
Sub-Awards Disbursed $199,019.00
Project Location - City Stanford
Project Location - State CA
Project Location - Zip Code 94305-4124
Project Location - Congressional District 18
Sub-Recipient DUNS Number 009214214
Sub-Recipient Address 450 SERRA MALL
Sub-Recipient City STANFORD
Sub-Recipient State California
Sub-Recipient Zip Code 94305-2004
Sub-Recipient Congressional District 18
Required To Report Top 5
Highly Compensated Officials
No

Sub-award CN-09CScha06-H (15-9766) - UNIVERSITY OF CALIFORNIA, SAN FRANCISCO

Sub-Award Amount $7,830,280
Sub-Award Date 02/26/2010
Sub-Awards Disbursed $6,387,119.87
Project Location - City San Francisco
Project Location - State CA
Project Location - Zip Code 94103-4249
Project Location - Congressional District 12
Sub-Recipient DUNS Number 094878337
Sub-Recipient Address 1855 FOLSOM ST STE 425
Sub-Recipient City SAN FRANCISCO
Sub-Recipient State California
Sub-Recipient Zip Code 94103-4249
Sub-Recipient Congressional District 12
Required To Report Top 5
Highly Compensated Officials
No


Vendor Transactions

Affymetrix, Inc. - Award Number 1RC2AG036607-01 - Affymetrix, Inc.

Award Number 1RC2AG036607-01
Sub-Award Number CN-09CScha06-H (15-9766)
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 95051-0704
Vendor Name Affymetrix, Inc.
Product and Service Description Genetitan DNA Analyzers, Other Med Supplies
Payment Amount $764,310

Affymetrix, Inc. - Award Number 1RC2AG036607-01 - Affymetrix, Inc.

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 95051-0704
Vendor Name Affymetrix, Inc.
Product and Service Description Other Med Supplies
Payment Amount $10,454,437

Apogent Discoveries DBA Matrix Technologies Corp - Award Number 1RC2AG036607-01 - Apogent Discoveries DBA Matrix Technologies Corp

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 03051-4900
Vendor Name Apogent Discoveries DBA Matrix Technologies Corp
Product and Service Description Other Med Supplies, Other Material/Supplies, Computer Supplies, Non-Capital Equipment
Payment Amount $154,399

BECKMAN COULTER - Award Number 1RC2AG036607-01 - BECKMAN COULTER

Award Number 1RC2AG036607-01
Sub-Award Number CN-09CScha06-H (15-9766)
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 92821-6232
Vendor Name BECKMAN COULTER
Product and Service Description 2 Biomek multichannel pippettors, Biomek Dual Arm System & Accessories
Payment Amount $682,247

Beckman Coulter Genomics - Award Number 1RC2AG036607-01 - Beckman Coulter Genomics

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 01923-2575
Vendor Name Beckman Coulter Genomics
Product and Service Description Other Med Supplies
Payment Amount $366,543

Beckman Coulter, Inc. - Award Number 1RC2AG036607-01 - Beckman Coulter, Inc.

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 60055-0164
Vendor Name Beckman Coulter, Inc.
Product and Service Description Other Med Supplies, Computer Supplies, Management Training
Payment Amount $397,028

BioMatrica, Inc. - Award Number 1RC2AG036607-01 - BioMatrica, Inc.

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 92121-3748
Vendor Name BioMatrica, Inc.
Product and Service Description Other Med Supplies
Payment Amount $86,848

Dasher Technologies - Award Number 1RC2AG036607-01 - Dasher Technologies

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 95008-5060
Vendor Name Dasher Technologies
Product and Service Description Data Precessing, Outside Services
Payment Amount $156,713

Dell Marketing, L.P. - Award Number 1RC2AG036607-01 - Dell Marketing, L.P.

Award Number 1RC2AG036607-01
Sub-Award Number CN-09CScha06-H (15-9766)
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 78682-0325
Vendor Name Dell Marketing, L.P.
Product and Service Description 20802085.58
Payment Amount $129,609

EMC CORPORATION - Award Number 1RC2AG036607-01 - EMC CORPORATION

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 01748-2209
Vendor Name EMC CORPORATION
Product and Service Description Computer Supplies, Data Processing Supplies
Payment Amount $115,929

ETI Group, Inc. - Award Number 1RC2AG036607-01 - ETI Group, Inc.

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 98370-7642
Vendor Name ETI Group, Inc.
Product and Service Description Outside Services
Payment Amount $26,500

Fisher Scientific - Award Number 1RC2AG036607-01 - Fisher Scientific

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 60693-0135
Vendor Name Fisher Scientific
Product and Service Description Other Med Supplies, Gloves, Freight & Storage
Payment Amount $166,368

Invitrogen Corp - Award Number 1RC2AG036607-01 - Invitrogen Corp

Award Number 1RC2AG036607-01
Sub-Award Number CN-09CScha06-H (15-9766)
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 92008-7321
Vendor Name Invitrogen Corp
Product and Service Description Genotyping Assays, Tag Polymerase
Payment Amount $226,852

KP Corporation - Award Number 1RC2AG036607-01 - KP Corporation

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 94579-3220
Vendor Name KP Corporation
Product and Service Description O/S Printing/Micro Services
Payment Amount $283,716

Labvantage Solutions Inc. - Award Number 1RC2AG036607-01 - Labvantage Solutions Inc.

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 08807-2931
Vendor Name Labvantage Solutions Inc.
Product and Service Description Computer Software>500
Payment Amount $93,600

ROCHE DIAGNOSTICS - Award Number 1RC2AG036607-01 - ROCHE DIAGNOSTICS

Award Number 1RC2AG036607-01
Sub-Award Number CN-09CScha06-H (15-9766)
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 46256-1025
Vendor Name ROCHE DIAGNOSTICS
Product and Service Description Ligh-cycler real-time PCR system, PCR Machine-4/23/10
Payment Amount $223,156

Rose International - Award Number 1RC2AG036607-01 - Rose International

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 94583-4210
Vendor Name Rose International
Product and Service Description Outside Services
Payment Amount $62,865

Tecan US Inc. - Award Number 1RC2AG036607-01 - Tecan US Inc.

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 27709-3953
Vendor Name Tecan US Inc.
Product and Service Description Expendable Equipment
Payment Amount $31,611

ThermoFisher - Award Number 1RC2AG036607-01 - ThermoFisher

Award Number 1RC2AG036607-01
Sub-Award Number CN-09CScha06-H (15-9766)
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 02454-9046
Vendor Name ThermoFisher
Product and Service Description Genotyping system and integration svc, VAL Genotyping & Integration System (final installment)
Payment Amount $472,044

Virtual Enterprises, Inc DBA Advanced System Group - Award Number 1RC2AG036607-01 - Virtual Enterprises, Inc DBA Advanced System Group

Award Number 1RC2AG036607-01
Sub-Award Number N/A
Vendor DUNS Number Not reported
Vendor HQ Zip Code + 4 80241-2415
Vendor Name Virtual Enterprises, Inc DBA Advanced System Group
Product and Service Description Computer Equip Maint, Computer Supplies
Payment Amount $154,952



Project Location Detail

Location Information
Latitude, Longitude 37º 48' 33", -122º 16' 4"
Congressional District 13
Address 1 2000 Broadway
Address 2
City Oakland
County Alameda
State CA
Zip 94612-2304
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